Dexmedetomidina por via epidural em gatas submetidas à ovariohisterectomia

Abstract

Dexmedetomidine is a drug in the alpha-2-adrenergic class, with specificity for α-2 receptors 10 times more potent, when compared to other drugs in this class. This sedative causes a decrease in heart rate in a dose-dependent manner. However, increasing the dose does not increase the intensity of sedation, on the other hand it prolongs the duration of the effects on the animal's body. Of the alpha-2 adrenergic drugs, dexmedetomidine causes a significant increase in blood pressure. It is still possible to notice, with the use of this drug, an increase in blood glycemia, since the alpha 2 agonists decrease the release of insulin in the bloodstream. A great advantage in the use of dexmedetomidine is the possibility of reversing its effects with the use of a specific antagonist, thus making anesthetic procedures safer when used. Epidural anesthesia, gives anesthetic procedures a more stable transoperative, since with its use it is possible to keep the patient in a more superficial anesthetic plane. Thus, the association of these anesthetics is extremely efficient in the practical routine of anesthetic protocols. Countless ovariohysterectomy procedures are performed on females of domestic cats, with the main purpose of the population control of these animals. Thus, we verified the importance of more studies related to different anesthetic protocols, which provide safe anesthesia and good analgesic potential for these procedures